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| 1526 | Clematises VII Declaration of War |  |
| Fought between the Habsburg Charles V, Spain and the Holy Roman Empire, & the League of Cognac, an Alliance including France, Pope Clement VII, the Republic of Venice, England, the Duchy of Milan & Florence |
| 1526 | Clematises VII League of Cognac | |
| Fought between the Habsburg Charles V, Spain and the Holy Roman Empire, & the League of Cognac, an Alliance including France, Pope Clement VII, the Republic of Venice, England, the Duchy of Milan & Florence |
| Shocked by the defeat of the French in the Italian War of 1521, Clement, together with the Republic of Venice, organizes an Alliance to drive the Habsburg powers-Spain and the Holy Roman Empire-from Italy |
| The League of Cognac is signed by Francis, Clement, Venice, Florence, and the Sforza of Milan, who desired to throw off the Imperial hegemony over them |
| 1529 | Clematises VII Rule of Cervia | |
| Sep Cervia Clement absolves the participants of the sack of Rome and promises to crown Charles, in return, he receives Ravenna and Cervia; cities which the Republic of Venice are forced to surrender |
| 1529 | Clematises VII Rule of Ravenna | |
| Sep Ravenna Clement absolves the participants of the sack of Rome and promises to crown Charles, in return, he receives Ravenna and Cervia; cities which the Republic of Venice are forced to surrender |
| 1526 | Clematises VII Siege of Lodi | |
| Lodi The League of Cognac quickly seizes Lodi, but Imperial troops march into Lombardy and soon force Sforza to abandon Milan |
| 1526 | Clematises VII Siege of Milan | |
| Milan The League of Cognac quickly seizes Lodi, but Imperial troops march into Lombardy and soon force Sforza to abandon Milan |
| 1527 | Clematises VII Siege of Rome | |
| Rome Francesco Guicciardini, in command of the Papal armies, proves unable to resist and when the Duke of Bourbon is killed, his underpaid army sack the city, forcing the Pope to flee |
| Sep Rome Clement absolves the participants of the sack of Rome and promises to crown Charles, in return, he receives Ravenna and Cervia; cities which the Republic of Venice are forced to surrender |
| 1529 | Clematises VII Treaty of Barcelona | |
| 29th June Barcelona Signs a treaty with Emperor Charles V settling their differences |
| 5th Aug Barcelona The final treaty, signed on August 5, removes France from the war, leaving Venice, Florence, and the Pope alone against Charles |
| 1530 | Ferruccio, Francesco Battle of Gavinana | |
| Sep Gavinana A Florentine army under Francesco Ferruccio engages the Imperials at the battle of Gavinana, but although Orange is killed, the Imperials win a decisive victory, and the Florentine Republic surrenders |
| 1530 | Ferruccio, Francesco Rule of Florentine Republic | |
| Sep Florentine Republic A Florentine army under Francesco Ferruccio engages the Imperials at the battle of Gavinana, but although Orange is killed, the Imperials win a decisive victory, and the Florentine Republic surrenders |
| 1530 | Medici, Alessandro de Rule of Florentine Republic | |
| Sep Florentine Republic Alessandro de' Medici is installed as Duke of Florence |
