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| Alliance Clement VII | |
| 22nd May Cognac Enters the Holy League of Cognac with France, Venice & Milan against Charles V |
| 22nd May Vatican Enters the Holy League of Cognac with France, Venice & Milan against Charles V |
| Capuchin Order Clementine VII | |
| Vatican Approves the foundation of the Capuchin Order |
| Declaration of War Clematises VII | |
| Fought between the Habsburg Charles V, Spain and the Holy Roman Empire, & the League of Cognac, an Alliance including France, Pope Clement VII, the Republic of Venice, England, the Duchy of Milan & Florence |
| League of Cognac Clematises VII | |
| Fought between the Habsburg Charles V, Spain and the Holy Roman Empire, & the League of Cognac, an Alliance including France, Pope Clement VII, the Republic of Venice, England, the Duchy of Milan & Florence |
| Shocked by the defeat of the French in the Italian War of 1521, Clement, together with the Republic of Venice, organizes an Alliance to drive the Habsburg powers-Spain and the Holy Roman Empire-from Italy |
| The League of Cognac is signed by Francis , Clement, Venice, Florence, and the Sforza of Milan, who desired to throw off the Imperial hegemony over them |
| Siege of Lodi Clematises VII | |
| Lodi The League of Cognac quickly seizes Lodi, but Imperial troops march into Lombardy and soon force Sforza to abandon Milan |
| Siege of Milan Clematises VII | |
| Milan The League of Cognac quickly seizes Lodi, but Imperial troops march into Lombardy and soon force Sforza to abandon Milan |