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| Discovery of Dominica Colombus, Christopher | |
| Discovers Dominica |
| Discovery of Guadalope Colombus, Christopher | |
| Guadalope Lands on Islands that will be called Guadalope |
| Discovery of Jamaica Colombus, Christopher | |
| 14th May Jamaica Discovers Jamaice & names the island Santiago, St James |
| Discovery of Marigalante Colombus, Christopher | |
| Discovers Marigalante |
| Discovery of Puerto Rico Colombus, Christopher | |
| Puerto Rico Discovers Puerto Rico |
| Discovery of Virgin Islands Colombus, Christopher | |
| Virgin Islands Lands in the Virgin Islands |
| Rule of Haiti Colombus, Christopher | |
| Isabella Founds the township of Isabella in Hispaniola, Haiti |
| Rule of Haiti Ferdinand II | |
| Isabella Colombus founds the township of Isabella in Hispaniola, Haiti |
| Rule of Naples Charles VIII | |
| Naples Spain, the Habsburgs, England & Italian states force Charles VIII to give up Naples |
| Treaty of Tordesillas Ferdinand II | |
| 7th June Tordesillas The Pope grants Spain exclusive rights to American land 250 leagues west of the Azores |
| Treaty of Tordessillas Isabella I the Catholic | |
| 4th May Tordessillas Establishes a line of demarcation between Spanish & Portuguese discoveries |
| 4th May Tordessillas Papal bull ratified by Alexander VI |